Ciara (name changed),a 13-year-old-girl from
, suffering from rarest of the rare complement deficiency genetic disease, C1q deficiency since the age of two, became the first teen in Asia suffering from a complex condition to receive a bone marrow transplant. Thanks to the team of doctors at Aster CMI Hospital, Bangalore, today is having a new lease of life. Ciara was suffering from repeated skin rashes and kidney ailments for over a decade and also developed difficulty in walking and stiffening of lower limbs. Until the transplant, Ciara was on multiple immune-suppressants to control the autoimmune condition – Systemic lupus erythematosus and was being treated with over 10 different medications for her severe skin disease, kidney disease and pulmonary hypertension.
Not just she was wheelchair bound, but also had very high risk of permanent renal failure till the Pediatric Immunology department at Aster CMI Hospital diagnosed her to have a very rare genetic disease – complement C1q deficiency as confirmed by the genetic studies conducted at the hospital. She was advised to undergo a bone marrow transplant and her father was found to be a full HLA match. He donated his bone marrow to Ciara and the teen has been cured to lead a normal life now. Currently, she is under medications and would require close follow-up for the next six months.
Currently, less than 10 such cases have been successfully transplanted in the world so far. The first one was conducted in UK in 2014. The transplant was carried out by the joint efforts of Dr Sagar Bhattad, Consultant, Pediatric Immunology and Rheumatology, Dr Stalin Ramprakash and Dr CP Raghuram, Consultants, Pediatric Hematology and BMT, Aster CMI Hospital, Bangalore.
Article Source: https://www.google.com/amp/s/healthcareradius.wordpress.com/2019/03/14/aster-cmi-rescues-teen-suffering-from-rare-genetic-disease/amp/